IONS Earnings Report, History & EPS Beat Rate.
Go beyond the headline. Compare expectations, history and the price reaction.
Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. IONS
Biotechnology · Updated 10/29/2026
EPS beats: 7 of 8 comparable reports. Positive price windows: 5 of 8.
Market caps may be up to 14 days old; prices up to seven days old; ratios and analyst estimates up to fourteen days old. Forward multiples use consensus for the fiscal year ending 2026-12-31, not the next 12 months. Negative or unavailable earnings multiples show “N/A”. Forward ADR multiples are omitted when the currency/share basis is not reconciled.
| Report date | EPS estimate | EPS actual | Surprise | Result | Revenue actual | Price window* | 5 sessions* |
|---|---|---|---|---|---|---|---|
| Jul 29 2026 | -1.09 | -0.69 | +36.7% | Beat | 268M | -3.7% | -2.0% |
| Apr 29 2026 | -0.85 | -0.56 | +34.1% | Beat | 246M | +4.2% | +7.1% |
| Feb 25 2026 | -1.24 | -1.41 | -14.0% | Miss | 203M | -5.7% | -7.0% |
| Oct 29 2025 | -1.15 | -0.61 | +47.0% | Beat | 156.72M | +0.8% | +1.5% |
| Jul 30 2025 | 0.27 | 0.86 | +218.5% | Beat | 452.05M | +3.6% | -1.9% |
| Apr 30 2025 | -1.11 | -0.75 | +32.4% | Beat | 131.61M | +6.4% | +10.9% |
| Feb 19 2025 | -1.09 | -0.66 | +39.4% | Beat | 226.58M | +2.3% | -0.6% |
| Nov 6 2024 | -1.16 | -0.95 | +18.1% | Beat | 133.81M | -0.9% | -2.6% |
*Adjusted close before the report date to the first (or fifth) trading close after it. This window can span two sessions and is not an isolated earnings-day return. Figures may be revised by the provider.
From earnings date
to informed research.
The calendar is the starting point. Put each earnings report in context before deciding what deserves a closer look.
What does the historical EPS beat rate mean?
The percentage of up to eight recent reports where actual EPS exceeded the analyst estimate. Missing estimates are excluded; meets are not beats. It measures earnings history, not investment wins or the chance a stock will rise.
How can I compare valuation before earnings?
Switch to Valuation to compare trailing and forward P/E and P/S. Open a company to see the fiscal year used for forward estimates, its one-year price chart and comparable companies’ recent earnings. Always compare similar accounting bases and business models.
Can I filter earnings before open or after close?
Yes. Use Release window to select before open, after close or time unconfirmed. Expected windows come from Nasdaq for near-term dates. Verify the final time on the company’s investor relations website.
Why can a stock fall after beating earnings?
Guidance, margins, valuation and what investors had already priced in can matter more than an EPS beat. Compare the reported result with the separate historical price windows; neither guarantees the next reaction.
Before the earnings release.
Explore the beat potential.
Will a company beat earnings expectations this quarter? We use market conditions, industry reporting, product releases and recent company news to inform our earnings predictions.
A clearer view before results
Put this quarter’s earnings expectations in context with the economic backdrop and market conditions.
An earnings beat does not guarantee a rising stock price. Predictions are not guarantees.